- Original Article
- Cardiology
- High antistreptolysin O titer is associated with coronary artery lesions in patients with Kawasaki disease
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Dong Eun Min, Do Hee Kim, Mi Young Han, Sung Ho Cha, Kyung Lim Yoon
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Clin Exp Pediatr. 2019;62(6):235-239. Published online November 7, 2018
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Purpose: In Kawasaki disease (KD) patients, coronary artery complications, incomplete and refractory types occur more frequently in patients with streptococcal or other bacterial/viral infections. Recently, we observed a higher incidence of coronary lesions in KD patients with high anti-streptolysin O (ASO) titer. Therefore, we hypothesized that KD patients diagnosed with concurrent streptococcal infection have poor prognosis, with respect to treatment... |
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- Review Article
- Update of genetic susceptibility in patients with Kawasaki disease
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Kyung Lim Yoon
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Clin Exp Pediatr. 2015;58(3):84-88. Published online March 20, 2015
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Kawasaki disease (KD) is an acute systemic vasculitis that predominantly affects children, and can result in coronary artery lesions (CAL). A patient with KD who is resistant to treatment with intravenous immunoglobulin (IVIG) has a higher risk of developing CAL. Incomplete KD has increased in prevalence in recent years, and is another risk factor for the development of CAL. Although... |
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- Original Article
- Analysis of clinical characteristics and causes of chest pain in children and adolescents
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Ji Hye Chun, Tae Hyeong Kim, Mi Young Han, Na Yeon Kim, Kyung Lim Yoon
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Clin Exp Pediatr. 2015;58(11):440-445. Published online November 22, 2015
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Purpose Chest pain is common in children and adolescents and is a reason for referral to pediatric cardiologists. Although most cases of chest pain in these age groups are benign and do not require treatment, timely diagnosis is important not to miss life-threatening diseases requiring prompt treatment. We investigated certain clinical characteristics that may be useful in the diagnosis of such... |
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- Case Report
- Two cases of female hydrocele of the canal of nuck
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Yu Mi Choi, Gyu Min Lee, Jung Bin Yi, Kyung Lim Yoon, Kye Shik Shim, Chong Woo Bae, Sung Il Choi, Hyun Cheol Kim
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Clin Exp Pediatr. 2012;55(4):143-146. Published online April 30, 2012
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The processus vaginalis within the inguinal canal forms the canal of Nuck, which is a homolog of the processus vaginalis in women. Incomplete obliteration of the processus vaginalis causes indirect inguinal hernia or hydrocele of the canal of Nuck, a very rare condition in women. Here, we report 2 cases of hydrocele of the canal of Nuck that were diagnosed... |
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- Original Article
- Transforming growth factor beta receptor II polymorphisms are associated with Kawasaki disease
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Yu Mi Choi, Kye Sik Shim, Kyung Lim Yoon, Mi Young Han, Sung Ho Cha, Su Kang Kim, Joo Ho Jung
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Clin Exp Pediatr. 2012;55(1):18-23. Published online January 31, 2012
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Purpose Transforming growth factor beta receptor 2 (TGFBR2) is a tumor suppressor gene that plays a role in the differentiation of striated cells and remodeling of coronary arteries. Single nucleotide polymorphisms (SNPs) of this gene are associated with Marfan syndrome and sudden death in patients with coronary artery disease. Cardiovascular remodeling and T cell activation of TGFBR2 gene suggest that the... |
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- Polymorphisms of methylenetetrahydrofolate reductase are not a risk factor for Kawasaki disease in the Korean population
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Kyung Lim Yoon, Jin Hee Ko, Kye Shik Shim, Mi Young Han, Sung Ho Cha, Su Kang Kim, Joo Ho Jung
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Clin Exp Pediatr. 2011;54(8):335-339. Published online August 31, 2011
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Purpose Hyperhomocysteinemia is known as a risk factor for atherosclerosis. Preclinical arteriosclerosis is noted and premature atherosclerosis is known to be accelerated in Kawasaki disease (KD) patients. Genetic polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene result in elevated plasma homocysteine concentrations and are known to be associated with the development of coronary artery disease. Our hypothesis is that single nucleotide polymorphisms... |
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- The relationship between catechol-O-methyltransferase gene polymorphism and
coronary artery abnormality in Kawasaki disease
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Hyo Jin Lee, Myung Sook Lee, Ji Sook Kim, Eun Ryoung Kim, Sung Wook Kang, Soo Kang Kim, Joo Ho Chun, Kyung Lim Yoon, Mi Young Han, Seong Ho Cha
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Clin Exp Pediatr. 2009;52(1):87-92. Published online January 15, 2009
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Purpose : Many gene polymorphisms are associated with coronary artery abnormalities in Kawasaki disease. Catechol-O- methyltransferase (COMT) plays an important role in the metabolism of catecholamines, catechol estrogen, and catechol drugs. Polymorphisms of the COMT gene are reported to be associated with myocardial infarction and coronary artery abnormalities. The aim of this study was to evaluate the relationship between COMT... |
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- Analysis of Risk Factors of Readmission to Hospital for Pediatric Asthma
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Kyung Lim Yoon, Young Ho Rah, Chong-Woo Bae, Sa Jun Chung
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Clin Exp Pediatr. 2000;43(4):556-560. Published online April 15, 2000
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Purpose : The admission rates for pediatric asthma are increasing annually and are partially responsible for the increased rates of readmission. Selections of children with a high-risk of readmission and aggressive treatments of them may improve treatment outcome and cost- effectiveness. The purpose of this study is to evaluate the risk factors affecting readmission in cases of bronchial asthma in... |
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